BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS

Novel bisphosphonate cyclic acetal compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating bone metabolism disorders, such as abnormal calcium and phosphate metabolism. La...

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Bibliographische Detailangaben
Hauptverfasser: MAZUR, ADAM WIESLAW, EBETINO, FRANK HALLOCK, DOBSON, ROY LEE MARTIN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Novel bisphosphonate cyclic acetal compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating bone metabolism disorders, such as abnormal calcium and phosphate metabolism. La présente invention concerne de nouveaux composés acétals cycliques bisphosphonates, ainsi que des procédés de préparation desdits composés, des compositions pharmaceutiques comprenant lesdits composés, et l'administration desdits composés dans des méthodes de traitement de troubles du métabolisme osseux, tels que le métabolisme anormal du calcium et du phosphate.