7-([1,2,4]TRIAZOLO[1,5-.ALPHA.]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF

Novel [1,2,4]triazolo [1, 5 - .alpha.] pyridinyl-6 -yl- substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SAI and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and c...

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Hauptverfasser: NACRO, KASSOUM, MOLINO, BRUCE F, LIU, SHUANG
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Novel [1,2,4]triazolo [1, 5 - .alpha.] pyridinyl-6 -yl- substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SAI and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-I and N-2 are also described in the present invention. La présente invention porte sur de nouvelles [l,2,4]triazolo[l,5-a]pyridinyl-6-yl-tétrahydroisoquinolines substituées. Ces composés et des formes cristallines SAl et N-2 sont utilisés dans le traitement de différents troubles neurologiques et physiologiques. L'invention porte également sur des procédés de fabrication de ces composés et des formes cristallines SA-I et N-2.