THICK FOAMS FOR BIOMEDICAL APPLICATIONS AND METHODS OF MAKING

There is described herein a method of making a polymer foam member having a thickness of greater than 1 cm, comprising the steps of: providing a thermoreversible polymer solution, said solution comprising a biocompatible, biodegradable polymer and a solvent; placing said solution in a mold; cooling...

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Bibliographische Detailangaben
Hauptverfasser: CHUN, IKSOO, HYLAND, THOMAS PATRICK, SHETTY, DHANURAJ S, VYAKARNAM, MURTY N
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:There is described herein a method of making a polymer foam member having a thickness of greater than 1 cm, comprising the steps of: providing a thermoreversible polymer solution, said solution comprising a biocompatible, biodegradable polymer and a solvent; placing said solution in a mold; cooling the solution in said mold to a precool temperature and holding the solution at said precool temperature for from 360 minutes to 1440 minutes until the solution gels; followed by removing the solvent by lyophilization to yield said foam member having a thickness of greater than 1 cm and inter-connected pores. Cette invention concerne un nouveau procédé de fabrication de mousses épaisses, en particulier des mousses épaisses moulées utilisées comme échafaudages tissulaires et autres dispositifs médicaux. L'invention concerne également de nouvelles mousses épaisses fabriquées avec le procédé de l'invention, lesdites mousses épaisses pouvant être utilisées comme dispositifs médicaux ou composants de dispositifs médicaux.