ANTAGONISTIC IL-17B RECEPTOR (IL-17BR) ANTIBODY

The invention provides antibody molecules which bind with high affinity and specificity to interleukin-17 receptor B (IL-17BR). Also provided is use of the antibody molecules for the treatment of diseases, such as asthma and inflammatory bowel disease, for example, ulcerative colitis or Crohn's...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	NEILL, DANIEL, MCKENZIE, ANDREW NEIL JAMES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides antibody molecules which bind with high affinity and specificity to interleukin-17 receptor B (IL-17BR). Also provided is use of the antibody molecules for the treatment of diseases, such as asthma and inflammatory bowel disease, for example, ulcerative colitis or Crohn's disease. L'invention porte sur un anticorps D9.2 et sur des molécules d'anticorps basées sur D9.2 qui se lient au récepteur B de l'interleukine 17. Ceux-ci peuvent être utiles en thérapie, par exemple dans le traitement de l'asthme, d'une colite ulcéreuse ou de la maladie de Crohn.