INHIBITORS OF BETA-SECRETASE

The present invention is directed to a compound represented by the following structural formula or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions and method of use of the compounds for inhibiting BACE activity in a subject are also provided. (see above formula) La présente i...

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Bibliographische Detailangaben
Hauptverfasser: CLAREMON, DAVID A, FUCHS, KLAUS, MCKEEVER, BRIAN, YUAN, JING, HEINE, NIKLAS, DILLARD, LAWRENCE W, XU, ZHENRONG, VENKATRAMAN, SHANKAR, WU, GUOSHENG, WU, ZHONGREN, LEFTHERIS, KATERINA, ZHENG, YAJUN, JIA, LANQI, MORALES-RAMOS, ANGEL, CACATIAN, SALVACION, SINGH, SURESH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention is directed to a compound represented by the following structural formula or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions and method of use of the compounds for inhibiting BACE activity in a subject are also provided. (see above formula) La présente invention concerne un composé représenté par la formule structurale suivante ou un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne en outre des compositions pharmaceutiques et des procédés d'utilisation des composés.