SELECTIVE INHIBITORS OF AKT AND METHODS OF USING SAME

The present invention describes an improved method for screening compounds for activity in inhibiting the enzymatic activity of Aktl protein kinase, also known as Protein Kinase B, an enzyme that is believed to playa key role in the inhibition of apoptosis and thus in the etiology of cancer and othe...

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Bibliographische Detailangaben
Hauptverfasser:	RONAI, ZE`EV, PELLECCHIA, MAURIZIO, CHIANG, GARY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	The present invention describes an improved method for screening compounds for activity in inhibiting the enzymatic activity of Aktl protein kinase, also known as Protein Kinase B, an enzyme that is believed to playa key role in the inhibition of apoptosis and thus in the etiology of cancer and other conditions, including neurodegenerative diseases.