METHODS AND COMPOSITIONS FOR USE OF A COCCIDIOSIS VACCINE

The present invention relates to a coccidiosis vaccine to protect poultry against Eimeria infection, comprising a recombinant avian adenovirus vector comprising in frame a (heterologous) promoter linked to a hydrophobic signal sequence for membrane anchoring, or linked to an hydrophobic secretion si...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: SHEPPARD, MICHAEL G
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to a coccidiosis vaccine to protect poultry against Eimeria infection, comprising a recombinant avian adenovirus vector comprising in frame a (heterologous) promoter linked to a hydrophobic signal sequence for membrane anchoring, or linked to an hydrophobic secretion signal and a cleavage site to allow secretion; a multiple cloning site for in frame insertion of an Eimeria antigen ORF such as derived from the r56, 82 kDa, and/or TFP250 antigens; a polyadenylation signal; and an avian adenovirus genome.