HETEROCYCLIC DERIVATIVES THAT MODULATE THE ACTIVITY OF STEAROYL-COA DESATURASE

HETEROCYCLIC DERIVATIVES THAT MODULATE THE ACTIVITY OF STEAROYL-COA DESATURASE

The present invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof, that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HOU, DUANJIE, DALES, NATALIE, FU, JIANMIN, KODUMURU, VISHNUMURTHY, ZHANG, ZAIHUI, POKROVSKAIA, NATALIA, SUN, SHAOYI
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof, that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed: R1-W¨P¨Q¨R2 (I).