PHARMACEUTICAL DEPOT COMPRISING N-{5-[(CYCLOPROPYLAMINO)CARBONYL]-2-METHYLPHENYL}-3-FLUORO-4-(PYRIDIN-2-YLMETHOXY)BENZAMIDE

PHARMACEUTICAL DEPOT COMPRISING N-{5-[(CYCLOPROPYLAMINO)CARBONYL]-2-METHYLPHENYL}-3-FLUORO-4-(PYRIDIN-2-YLMETHOXY)BENZAMIDE

A pharmaceutical depot comprising (i) N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is relea...

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Bibliographische Detailangaben
Hauptverfasser: BATEMAN, NICOLA FRANCES, MACFAUL, PHILIP ALEXANDER, NASH, IAN ALUN
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:A pharmaceutical depot comprising (i) N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation.