NUCLEOSIDE DERIVATIVES FOR TREATMENT OF CALICIVIRIDAE INFECTIONS, INCLUDING NOROVIRUS INFECTIONS

A method and composition for treating a host infected with a Caliciviridae virus, such as a Norovirus, comprising administering an effective treatment amount of a described modified nucleoside or a pharmaceutically acceptable salt thereof, is provided. The composition comprises a pyrimidine compound...

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Bibliographische Detailangaben
Hauptverfasser:	SCHINAZI, RAYMOND F, COATS, STEVEN J, WHITAKER, RICHARD ANTHONY, MCBRAYER, TAMARA ROSARIO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	A method and composition for treating a host infected with a Caliciviridae virus, such as a Norovirus, comprising administering an effective treatment amount of a described modified nucleoside or a pharmaceutically acceptable salt thereof, is provided. The composition comprises a pyrimidine compound of the general formula: (see above formula) La présente invention concerne un procédé et une composition permettant de traiter un hôte infecté par un virus Caliciviridae, tel quun norovirus, comprenant ladministration dune quantité de traitement efficace dun nucléoside modifié décrit ou dun sel pharmaceutiquement acceptable de celui-ci.