ANTITUMOR AGENT

ANTITUMOR AGENT

Disclosed is a novel antitumor agent containing, as an active ingredient, a compound inhibiting binding between an acetylated histone and a bromodomain-containing protein, preferably a thienotriazolodiazepine compound represented by the general formula (I) below or a pharmaceutically acceptable salt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OOIKE, SHINSUKE, SUGAHARA, KUNIO, IWATA, KAZUNORI, MIYOSHI, SHINJI, HIKAWA, HIDEMASA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed is a novel antitumor agent containing, as an active ingredient, a compound inhibiting binding between an acetylated histone and a bromodomain-containing protein, preferably a thienotriazolodiazepine compound represented by the general formula (I) below or a pharmaceutically acceptable salt thereof, or a hydrate or solvate of any of those. (In the formula, the symbols are as defined in the description.)