SYNTHESIS OF IODIXANOL IN WATER
This invention relates to the synthesis of iodixanol (1,3-bis(acetamido)-N,N'- bis[3,5-bis(2,3- dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the dimerisation of 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo- isophthalamide with water...
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Zusammenfassung: | This invention relates to the synthesis of iodixanol (1,3-bis(acetamido)-N,N'- bis[3,5-bis(2,3- dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the dimerisation of 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo- isophthalamide with water as solvent.
La présente invention concerne la synthèse diodixanol(1,3-bis(acétamido)-N,N- bis[3,5-bis(2,3- dihydroxypropylaminocarbonyl)-2,4,6-triiodophényl]-2-hydroxypropane), plus particulièrement la dimérisation du 5-acétamido-N,N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophtalamide avec leau comme solvant. |
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