4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS

The present teachings relate to 4-imidazolidinones of Formula (I) Insert formula here as it appears in written form in the specification (I) which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present teachings further relate to compositions...

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Hauptverfasser: JANUSZ, JOHN MICHAEL, LEE, WENLIN, RIDGEWAY, JAMES MADISON, II, JACKSON, CHRISTOPHER M, FLUXE, ANDREW J, WHITE, RONALD E, FAIRWEATHER, NEIL, COBURN, KEITH, BLASS, BENJAMIN ERIC, WU, SHENGDE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present teachings relate to 4-imidazolidinones of Formula (I) Insert formula here as it appears in written form in the specification (I) which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present teachings further relate to compositions and methods for treating atrial-selective antiarrhythmia.