PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE

A method of crosslinking a protein or peptide for use as a biomaterial, the method comprising the step of irradiating a photoactivatable metal-ligand complex and an electron acceptor in the presence of the protein or peptide, thereby initiating a crosslinking reaction to form a 3-dimensional matrix...

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Hauptverfasser: BROWNLEE, ALAN GEORGE, ELVIN, CHRISTOPHER MALCOLM, LINDALL, CHARLES MARK, WERKMEISTER, JEROME ANTHONY, RAMSHAW, JOHN ALAN MAURICE
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creator BROWNLEE, ALAN GEORGE
ELVIN, CHRISTOPHER MALCOLM
LINDALL, CHARLES MARK
WERKMEISTER, JEROME ANTHONY
RAMSHAW, JOHN ALAN MAURICE
description A method of crosslinking a protein or peptide for use as a biomaterial, the method comprising the step of irradiating a photoactivatable metal-ligand complex and an electron acceptor in the presence of the protein or peptide, thereby initiating a crosslinking reaction to form a 3-dimensional matrix of the biomaterial. L'invention porte sur un procédé de réticulation d'une protéine ou d'un peptide destiné à être utilisé comme biomatériau. Le procédé consiste à irradier un complexe métal-ligand photoactivable et un accepteur d'électrons en présence de la protéine ou du peptide, ce qui permet d'amorcer une réaction de réticulation afin de former une matrice tridimensionnelle du biomatériau.
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language eng ; fre
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subjects ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE
ADHESIVES
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
DYES
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
PAINTS
POLISHES
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF MATERIALS AS ADHESIVES
title PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE
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