PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE

A method of crosslinking a protein or peptide for use as a biomaterial, the method comprising the step of irradiating a photoactivatable metal-ligand complex and an electron acceptor in the presence of the protein or peptide, thereby initiating a crosslinking reaction to form a 3-dimensional matrix...

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Bibliographische Detailangaben
Hauptverfasser:	BROWNLEE, ALAN GEORGE, ELVIN, CHRISTOPHER MALCOLM, LINDALL, CHARLES MARK, WERKMEISTER, JEROME ANTHONY, RAMSHAW, JOHN ALAN MAURICE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE ADHESIVES CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR DYES HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NATURAL RESINS NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL ORGANIC MACROMOLECULAR COMPOUNDS PAINTS POLISHES THEIR PREPARATION OR CHEMICAL WORKING-UP USE OF MATERIALS AS ADHESIVES
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Beschreibung
Zusammenfassung:	A method of crosslinking a protein or peptide for use as a biomaterial, the method comprising the step of irradiating a photoactivatable metal-ligand complex and an electron acceptor in the presence of the protein or peptide, thereby initiating a crosslinking reaction to form a 3-dimensional matrix of the biomaterial. L'invention porte sur un procédé de réticulation d'une protéine ou d'un peptide destiné à être utilisé comme biomatériau. Le procédé consiste à irradier un complexe métal-ligand photoactivable et un accepteur d'électrons en présence de la protéine ou du peptide, ce qui permet d'amorcer une réaction de réticulation afin de former une matrice tridimensionnelle du biomatériau.