ALTERNATIVE DIMERISATION REAGENTS FOR SYNTHESIS OF IODIXANOL

ALTERNATIVE DIMERISATION REAGENTS FOR SYNTHESIS OF IODIXANOL

This invention relates generally to non-ionic X-ray contrast agents. It further relates to the synthesis of iodixanol. In particular, it relates to alternative dimerisation reagents in the conversion of 5-acetamido-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide ("Compound A&quo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DUGSTAD, HARALD, GULBRANDSEN, TRYGVE, BERG, ARNE, GACEK, MICHEL, STRANDE, PER
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention relates generally to non-ionic X-ray contrast agents. It further relates to the synthesis of iodixanol. In particular, it relates to alternative dimerisation reagents in the conversion of 5-acetamido-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide ("Compound A") to iodixanol.