A METHOD FOR SUSTAINABLE TRANSGENE TRANSCRIPTION

The present invention relates to constructs and methods for improving exp ression of transgenes in plants, animals and humans by including introns in the transcript to limit the exon sizes to less than about 60 bp. In the occu rrence of dsRNA formation, methylation of the nuclear transgene construct...

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1. Verfasser: OOSTHUYSE, BERT WIM
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to constructs and methods for improving exp ression of transgenes in plants, animals and humans by including introns in the transcript to limit the exon sizes to less than about 60 bp. In the occu rrence of dsRNA formation, methylation of the nuclear transgene construct DN A sequences and transcriptional silencing is not induced.