OPTIMIZED NUCLEOTIDE SEQUENCES OF VB6-845 FOR EXPRESSION OF RECOMBINANT PROTEINS

An optimized nucleic acid sequence encoding the immunoconjugate VB6-845 i s described Modifications to the original VB6-845 include changes in the nuc leic acid sequence encoding the VH region, CH region, CL region, VL region, the furm linker and the bouganm toxin. The optimized VB6-845 displays imp...

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Hauptverfasser:	MACDONALD, GLEN CHRISTOPHER, CIZEAU, JEANNICK
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	An optimized nucleic acid sequence encoding the immunoconjugate VB6-845 i s described Modifications to the original VB6-845 include changes in the nuc leic acid sequence encoding the VH region, CH region, CL region, VL region, the furm linker and the bouganm toxin. The optimized VB6-845 displays improv ed recombinant protein expression over the original in an E.coli expression system.