QUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FOR SELECTIN INHIBITION

The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teach ings can act as antagonists of the mammalian adhesion proteins known as sele ctins. Methods for treating or preventing selectin-mediated disorders are...

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Bibliographische Detailangaben
Hauptverfasser: JANZ, KRISTIN MARIE, BEDARD, PATRICIA WARD, MORETTO, ALESSANDRO FABIO, HUANG, ADRIAN, KAILA, NEELU
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teach ings can act as antagonists of the mammalian adhesion proteins known as sele ctins. Methods for treating or preventing selectin-mediated disorders are pr ovided, which include administration of these compounds in a therapeutically effective amount.