SUBSTITUTED 5H-PYRIMIDO[5,4-B]INDOLES, PROCESSES FOR THE PRODUCTION THEREOF AND THEIR USE FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE HEMATOPOIETIC SYSTEM

SUBSTITUTED 5H-PYRIMIDO[5,4-B]INDOLES, PROCESSES FOR THE PRODUCTION THEREOF AND THEIR USE FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE HEMATOPOIETIC SYSTEM

The invention relates to compounds of general formula 1 (see formula 1) to processes for the production thereof, to pharmaceutical preparations containing said compounds and/or physiologically compatible salts and/or solvates which can be produced therefrom as well as to the pharmaceutical use of sa...

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Bibliographische Detailangaben
Hauptverfasser: HERMANN, KONRAD, SCHULZE, ALEXANDER, MUGRIDGE, KENNETH, DEANGELO, JOSEPH, REICHELT, CLAUDIA, HEINICKE, JOCHEN, LETSCHERT, SVEN, DAGHISH, MOHAMMED, LUDWIG, ALEXANDER, SHUSTER, MAJ
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The invention relates to compounds of general formula 1 (see formula 1) to processes for the production thereof, to pharmaceutical preparations containing said compounds and/or physiologically compatible salts and/or solvates which can be produced therefrom as well as to the pharmaceutical use of said compounds, the salts or solvates thereof as inductors of apoptosis in the case of non-solid malignant tumors of the hematopoietic system, in particular in the case of leukemias and lymphomas, more particularly in the case of leukemic B lymphocytes.