BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS

The invention relates to bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of cancer, proliferative disorders, or a disease state or condition mediated by a FGFR kinase, the compound having the struc...

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Hauptverfasser: NIJJAR, RAJDEEP KAUR, GILL, ADRIAN LIAM, VICKERSTAFFE, EMMA, TAYLOR, RICHARD DAVID, BESONG, GILBERT EBAI, MURRAY, CHRISTOPHER WILLIAM, CALLAGHAN, OWEN, SAXTY, GORDON, BERDINI, VALERIO, O'BRIEN, MICHAEL ALISTAIR, CONGREVE, MILES STUART, CARR, MARIA GRAZIA, PIKE, ANDREW, GRIFFITHS-JONES, CHARLOTTE MARY, MADIN, ANDREW
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of cancer, proliferative disorders, or a disease state or condition mediated by a FGFR kinase, the compound having the structure of Formula (I). (see formula I) L'invention concerne de nouveaux composés dérivés hétérocycliques bicycliques, des compositions pharmaceutiques comprenant lesdits composés et l'utilisation desdits composés dans le traitement de maladies, par exemple d'un cancer.