ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE

The present invention is directed to aryl sulfamide derivatives of formul a (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer there of, which are monoamine reuptake inhibitors, compositions containing these d erivatives, and methods of their use for the prevention and treatment of...

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Hauptverfasser: MC COMAS, CASEY CAMERON, CRAWLEY, MATTHEW L, ZHANG, PUWEN, MAHANEY, PAIGE ERIN, VU, AN THIEN, COHN, STEPHEN TODD, KIM, CALLAIN YOUNGHEE, WOODWORTH, RICHARD PAGE, JR, MANN, CHARLES WILLIAM, FENSOME, ANDREW, TRYBULSKI, EUGENE JOHN, MARELLA, MICHAEL ANTHONY, GOLDBERG, JOEL ADAM, SABATUCCI, JOSEPH P, TEREFENKO, EUGENE ANTHONY, JENKINS, DOUGLAS JOHN, O'NEILL, DAVID JOHN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention is directed to aryl sulfamide derivatives of formul a (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer there of, which are monoamine reuptake inhibitors, compositions containing these d erivatives, and methods of their use for the prevention and treatment of con ditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gast rointestinal disorders and genitourinary disorder, depression disorders, end ogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain , and other diseases or disorders.