OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS

Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are al...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GARRISON, ROBBI J, SHUKLA, VIPULA K, MITCHELL, JON C, URNOV, FYODOR, BLUE, RYAN C, WORDEN, SARAH E, PETOLINO, JOSEPH F, CAI, QIHUA C, BAKER, LISA W, MILLER, JEFFREY, ARNOLD, NICOLE L
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	GARRISON, ROBBI J SHUKLA, VIPULA K MITCHELL, JON C URNOV, FYODOR BLUE, RYAN C WORDEN, SARAH E PETOLINO, JOSEPH F CAI, QIHUA C BAKER, LISA W MILLER, JEFFREY ARNOLD, NICOLE L
description	Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described L'invention concerne des doigts de zinc comprenant des résidus de coordination de zinc CCHC. L'invention concerne également des protéines à doigts de zinc et des protéines hybrides comprenant ces doigts de zinc CCHC ainsi que des polynucléotides codant pour ces protéines. Elle se rapporte en outre à des méthodes d'utilisation de ces protéines pour l'édition de gènes et la régulation de gènes.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2669746C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2669746C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2669746C3</originalsourceid><addsrcrecordid>eNrjZNDxDwjx9PWMcnVR8PP303V2BJKezo4-ClGefs4Kbp5-7q5BCgFB_iGunn7BPAysaYk5xam8UJqbQd7NNcTZQze1ID8-tbggMTk1L7Uk3tnRyMzM0tzEzNmYsAoAF-ckgQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS</title><source>esp@cenet</source><creator>GARRISON, ROBBI J ; SHUKLA, VIPULA K ; MITCHELL, JON C ; URNOV, FYODOR ; BLUE, RYAN C ; WORDEN, SARAH E ; PETOLINO, JOSEPH F ; CAI, QIHUA C ; BAKER, LISA W ; MILLER, JEFFREY ; ARNOLD, NICOLE L</creator><creatorcontrib>GARRISON, ROBBI J ; SHUKLA, VIPULA K ; MITCHELL, JON C ; URNOV, FYODOR ; BLUE, RYAN C ; WORDEN, SARAH E ; PETOLINO, JOSEPH F ; CAI, QIHUA C ; BAKER, LISA W ; MILLER, JEFFREY ; ARNOLD, NICOLE L</creatorcontrib><description>Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described L'invention concerne des doigts de zinc comprenant des résidus de coordination de zinc CCHC. L'invention concerne également des protéines à doigts de zinc et des protéines hybrides comprenant ces doigts de zinc CCHC ainsi que des polynucléotides codant pour ces protéines. Elle se rapporte en outre à des méthodes d'utilisation de ces protéines pour l'édition de gènes et la régulation de gènes.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170516&DB=EPODOC&CC=CA&NR=2669746C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170516&DB=EPODOC&CC=CA&NR=2669746C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GARRISON, ROBBI J</creatorcontrib><creatorcontrib>SHUKLA, VIPULA K</creatorcontrib><creatorcontrib>MITCHELL, JON C</creatorcontrib><creatorcontrib>URNOV, FYODOR</creatorcontrib><creatorcontrib>BLUE, RYAN C</creatorcontrib><creatorcontrib>WORDEN, SARAH E</creatorcontrib><creatorcontrib>PETOLINO, JOSEPH F</creatorcontrib><creatorcontrib>CAI, QIHUA C</creatorcontrib><creatorcontrib>BAKER, LISA W</creatorcontrib><creatorcontrib>MILLER, JEFFREY</creatorcontrib><creatorcontrib>ARNOLD, NICOLE L</creatorcontrib><title>OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS</title><description>Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described L'invention concerne des doigts de zinc comprenant des résidus de coordination de zinc CCHC. L'invention concerne également des protéines à doigts de zinc et des protéines hybrides comprenant ces doigts de zinc CCHC ainsi que des polynucléotides codant pour ces protéines. Elle se rapporte en outre à des méthodes d'utilisation de ces protéines pour l'édition de gènes et la régulation de gènes.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDxDwjx9PWMcnVR8PP303V2BJKezo4-ClGefs4Kbp5-7q5BCgFB_iGunn7BPAysaYk5xam8UJqbQd7NNcTZQze1ID8-tbggMTk1L7Uk3tnRyMzM0tzEzNmYsAoAF-ckgQ</recordid><startdate>20170516</startdate><enddate>20170516</enddate><creator>GARRISON, ROBBI J</creator><creator>SHUKLA, VIPULA K</creator><creator>MITCHELL, JON C</creator><creator>URNOV, FYODOR</creator><creator>BLUE, RYAN C</creator><creator>WORDEN, SARAH E</creator><creator>PETOLINO, JOSEPH F</creator><creator>CAI, QIHUA C</creator><creator>BAKER, LISA W</creator><creator>MILLER, JEFFREY</creator><creator>ARNOLD, NICOLE L</creator><scope>EVB</scope></search><sort><creationdate>20170516</creationdate><title>OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS</title><author>GARRISON, ROBBI J ; SHUKLA, VIPULA K ; MITCHELL, JON C ; URNOV, FYODOR ; BLUE, RYAN C ; WORDEN, SARAH E ; PETOLINO, JOSEPH F ; CAI, QIHUA C ; BAKER, LISA W ; MILLER, JEFFREY ; ARNOLD, NICOLE L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2669746C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>GARRISON, ROBBI J</creatorcontrib><creatorcontrib>SHUKLA, VIPULA K</creatorcontrib><creatorcontrib>MITCHELL, JON C</creatorcontrib><creatorcontrib>URNOV, FYODOR</creatorcontrib><creatorcontrib>BLUE, RYAN C</creatorcontrib><creatorcontrib>WORDEN, SARAH E</creatorcontrib><creatorcontrib>PETOLINO, JOSEPH F</creatorcontrib><creatorcontrib>CAI, QIHUA C</creatorcontrib><creatorcontrib>BAKER, LISA W</creatorcontrib><creatorcontrib>MILLER, JEFFREY</creatorcontrib><creatorcontrib>ARNOLD, NICOLE L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GARRISON, ROBBI J</au><au>SHUKLA, VIPULA K</au><au>MITCHELL, JON C</au><au>URNOV, FYODOR</au><au>BLUE, RYAN C</au><au>WORDEN, SARAH E</au><au>PETOLINO, JOSEPH F</au><au>CAI, QIHUA C</au><au>BAKER, LISA W</au><au>MILLER, JEFFREY</au><au>ARNOLD, NICOLE L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS</title><date>2017-05-16</date><risdate>2017</risdate><abstract>Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described L'invention concerne des doigts de zinc comprenant des résidus de coordination de zinc CCHC. L'invention concerne également des protéines à doigts de zinc et des protéines hybrides comprenant ces doigts de zinc CCHC ainsi que des polynucléotides codant pour ces protéines. Elle se rapporte en outre à des méthodes d'utilisation de ces protéines pour l'édition de gènes et la régulation de gènes.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng ; fre
recordid	cdi_epo_espacenet_CA2669746C
source	esp@cenet
subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
title	OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T17%3A02%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GARRISON,%20ROBBI%20J&rft.date=2017-05-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2669746C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true