METHOD OF ISOLATING BIOMACROMOLECULES USING LOW PH AND DIVALENT CATIONS

The present invention is related to a method of isolating a biological ma cromolecule in a composition. Specifically, the present invention is directe d to a method of isolating a biomacromolecule in a composition containing an impurity, the method comprising (a) lowering the pH of the composition,...

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Hauptverfasser:	DE VILMORIN, PHILIPPE GEORGES, ROMERO, JONATHAN, CHROSTOWSKI, JAMES, CASE, JENNIFER YUN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention is related to a method of isolating a biological ma cromolecule in a composition. Specifically, the present invention is directe d to a method of isolating a biomacromolecule in a composition containing an impurity, the method comprising (a) lowering the pH of the composition, (b) adding a divalent cation to the composition, and (c) separating the biomacr omolecule from the impurity.