THERAPEUTIC COMPOUNDS

The invention relates to a method of improving oral drug absorption of ad enosine analogues by the use of 2',3'-methylidene acetal adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further rel ates to compounds that are prodrugs of adenosine receptor agoni...

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Bibliographische Detailangaben
1. Verfasser:	SAVORY, EDWARD DANIEL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The invention relates to a method of improving oral drug absorption of ad enosine analogues by the use of 2',3'-methylidene acetal adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further rel ates to compounds that are prodrugs of adenosine receptor agonists, and to t heir use as therapeutic compounds, in particular as analgesic or anti-inflam matory compounds, or as disease modifying antirheumatic drugs (DMARDs), and to methods of preventing, treating or ameliorating pain or inflammation usin g these compounds.