SUBSTITUTED AMINOPYRAZOLOPYRIDINES AND SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
The invention relates to substituted aminopyrazolopyridines according to the general formula (I) : in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts thereof, to pharmaceutical compositi ons comprising said substituted aminopyrazolopyridines, to methods of prep...
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| creator | THIERAUCH, KARL-HEINZ TER LAAK, ANTONIUS M INCE, STUART HARTUNG, INGO BRIEM, HANS KETTSCHAU, GEORG SCHWEDE, WOLFGANG |
| description | The invention relates to substituted aminopyrazolopyridines according to the general formula (I) : in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts thereof, to pharmaceutical compositi ons comprising said substituted aminopyrazolopyridines, to methods of prepar ing said substituted aminopyrazolopyridines as well as the use thereof for m anufacturing a pharmaceutical composition for the treatment of diseases of d ysregulated vascular growth or of diseases which are accompanied with dysreg ulated vascular growth, wherein the compounds effectively interfere with Tie 2 signalling. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SUBSTITUTED AMINOPYRAZOLOPYRIDINES AND SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
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