ADMINISTRATION OF THE REG1 ANTICOAGULATION SYSTEM

An improved method of administration of an aptamer and antidote system to regulate blood coagulation in a host is provided based on weight adjusted o r body mass index-adjusted dosing of the components of the system to provide a desired pharmacodynamic response. In addition, a method of reversing ac...

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Hauptverfasser:	RUSCONI, CHRISTOPHER P, TONKENS, ROSS M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	An improved method of administration of an aptamer and antidote system to regulate blood coagulation in a host is provided based on weight adjusted o r body mass index-adjusted dosing of the components of the system to provide a desired pharmacodynamic response. In addition, a method of reversing acti vity of the aptamer to a desired extent is provided where an antidote dose i s based solely on its relationship to the aptamer dose.