MODIFIED HUMANISED ANTI-INTERLEUKIN-18 ANTIBODIES

The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential. La présente invention concerne...

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Bibliographische Detailangaben
Hauptverfasser:	ELLIS, JONATHAN HENRY, HAMBLIN, PAUL ANDREW, GERMASCHEWSKI, VOLKER, KIRBY, IAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential. La présente invention concerne des anticorps anti-IL-18 humanisés, des procédés de fabrication et des procédés de traitement impliquant lesdits anticorps. L'invention concerne en outre des procédés de criblage qui utilisent, par exemple, la résonance plasmon de surface pour identifier des anticorps présentant des potentialités thérapeutiques.