NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION
The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation...
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| creator | SANN, HOLGER BENSON, WERNER SMID, PETER PREUSCHOFF, ULF BRUCKNER, REINHARD REICHE, DANIA FIRNGES, MICHAEL JASSERAND, DANIEL MCCREARY, ANDREW CHRISTOPHER MENTZEL, MATTHIAS ATTALI, AMOS JAUNZEMS, JANIS ADOLFS, MARTINUS SCHON, UWE |
| description | The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation of the novel dual NK2/NK3-antagonists and to their uses.
La présente invention concerne des nouveaux antagonistes doubles de NK2/NK3 de formule (I) dans laquelle la signification de X et celle de R1 à R5 est telle que définie dans les revendications et dans la description. L'invention concerne également des compositions pharmaceutiques comprenant ces composés. En outre, l'invention concerne des procédés de préparation des nouveaux antagonistes doubles de NK2/NK3 et leurs utilisations. |
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La présente invention concerne des nouveaux antagonistes doubles de NK2/NK3 de formule (I) dans laquelle la signification de X et celle de R1 à R5 est telle que définie dans les revendications et dans la description. L'invention concerne également des compositions pharmaceutiques comprenant ces composés. En outre, l'invention concerne des procédés de préparation des nouveaux antagonistes doubles de NK2/NK3 et leurs utilisations.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070809&DB=EPODOC&CC=CA&NR=2641817A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070809&DB=EPODOC&CC=CA&NR=2641817A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SANN, HOLGER</creatorcontrib><creatorcontrib>BENSON, WERNER</creatorcontrib><creatorcontrib>SMID, PETER</creatorcontrib><creatorcontrib>PREUSCHOFF, ULF</creatorcontrib><creatorcontrib>BRUCKNER, REINHARD</creatorcontrib><creatorcontrib>REICHE, DANIA</creatorcontrib><creatorcontrib>FIRNGES, MICHAEL</creatorcontrib><creatorcontrib>JASSERAND, DANIEL</creatorcontrib><creatorcontrib>MCCREARY, ANDREW CHRISTOPHER</creatorcontrib><creatorcontrib>MENTZEL, MATTHIAS</creatorcontrib><creatorcontrib>ATTALI, AMOS</creatorcontrib><creatorcontrib>JAUNZEMS, JANIS</creatorcontrib><creatorcontrib>ADOLFS, MARTINUS</creatorcontrib><creatorcontrib>SCHON, UWE</creatorcontrib><title>NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION</title><description>The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation of the novel dual NK2/NK3-antagonists and to their uses.
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La présente invention concerne des nouveaux antagonistes doubles de NK2/NK3 de formule (I) dans laquelle la signification de X et celle de R1 à R5 est telle que définie dans les revendications et dans la description. L'invention concerne également des compositions pharmaceutiques comprenant ces composés. En outre, l'invention concerne des procédés de préparation des nouveaux antagonistes doubles de NK2/NK3 et leurs utilisations.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION |
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