NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION

The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation...

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Hauptverfasser:	SANN, HOLGER, BENSON, WERNER, SMID, PETER, PREUSCHOFF, ULF, BRUCKNER, REINHARD, REICHE, DANIA, FIRNGES, MICHAEL, JASSERAND, DANIEL, MCCREARY, ANDREW CHRISTOPHER, MENTZEL, MATTHIAS, ATTALI, AMOS, JAUNZEMS, JANIS, ADOLFS, MARTINUS, SCHON, UWE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation of the novel dual NK2/NK3-antagonists and to their uses. La présente invention concerne des nouveaux antagonistes doubles de NK2/NK3 de formule (I) dans laquelle la signification de X et celle de R1 à R5 est telle que définie dans les revendications et dans la description. L'invention concerne également des compositions pharmaceutiques comprenant ces composés. En outre, l'invention concerne des procédés de préparation des nouveaux antagonistes doubles de NK2/NK3 et leurs utilisations.