DRUG DELIVERY SYSTEM FOR BIOADHESION TO A VULVOVAGINAL SURFACE

A pharmaceutical composition comprises a first active (e.g., antibacterial) agent and a second (e.g., antifungal) active agent, and comprises a component that is adapted for bioadhesion to a vulvovaginal surface. The composition provides differential release of the active agents at such a surface, w...

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Bibliographische Detailangaben
Hauptverfasser: LEVINSON, R. SAUL, BORTZ, JONATHAN
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:A pharmaceutical composition comprises a first active (e.g., antibacterial) agent and a second (e.g., antifungal) active agent, and comprises a component that is adapted for bioadhesion to a vulvovaginal surface. The composition provides differential release of the active agents at such a surface, wherein the second active agent exhibits a release profile that is substantially delayed, extended and/or inverted relative to the release profile of the first active agent.