TRANSDERMAL THERAPEUTIC SYSTEM FOR VOLATILE AND/OR THERMOLABILE SUBSTANCES

The present invention relates to a transdermal therapeutic system comprising at least one readily volatile and/or thermolabile active ingredient and/or auxiliary, which can be produced by laminating at least three components onto one another, namely a polymeric matrix layer, a likewise polymeric acc...

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Bibliographische Detailangaben
Hauptverfasser: HORSTMANN, MICHAEL, DZEKAN, HORST, JUNG, TOBIAS
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to a transdermal therapeutic system comprising at least one readily volatile and/or thermolabile active ingredient and/or auxiliary, which can be produced by laminating at least three components onto one another, namely a polymeric matrix layer, a likewise polymeric acceptor layer that absorbs the active ingredient and/or auxiliary at an increased rate, and a donor layer comprising, at the point of production, the volatile and/or thermolabile active ingredient and/or auxiliary. The system according to the invention is characterized in that, during or shortly after the lamination process, the donor layer combines with the acceptor layer as a result of migration of the readily volatile and/or thermolabile substances.