COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPTICEMIA, TRANSGENIC CELL LINE THAT PRODUCES ERYTHROPOIETIN GLYCOISOFORMS, PHARMACEUTICAL COMPOSITION COMPRISING SAID COMBINATION

The invention relates to a combination of erythropoietin glycoisoforms, in which said glycoisoforms can comprise between 4 and 10 sialic acid molecules per molecule of erythropoietin. The aforementioned combination of glycoisoforms can be used for the treatment or prevention of septicemia/sepsis. Th...

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Hauptverfasser: ETCHEVERRIGARAY, MARINA, PEREIRA BACCI, DARDO ALEXIS, DAELLI, MARCELO GUSTAVO, DIDIER, CAROLINA, PEREIRO, MIRIAM PATRICIA, AMADEO, GABRIEL IGNACIO, MASKIN, NESTOR, ARTANA, CRISTINA NOEMI, PISTILLO, BERNARDO CESAR, KRATJE, RICARDO, LOPEZ, RICARDO AGUSTIN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to a combination of erythropoietin glycoisoforms, in which said glycoisoforms can comprise between 4 and 10 sialic acid molecules per molecule of erythropoietin. The aforementioned combination of glycoisoforms can be used for the treatment or prevention of septicemia/sepsis. The invention also relates to a pharmaceutical composition comprising the above-mentioned combination, a cell line that produces a combination of erythropoietin glycoisoforms, methods of obtaining the cell line, a method of producing the combination of glycoisoforms and methods for the treatment and prevention of septicemia/sepsis.