ANTI-MALARIAL COMPOUND ISOLATED FROM GOMPHOSTEMA NIVEUM

The present invention provides an antimalarial compound 3-[2-(2-Hydroxymethyl-1,4a,5-trimethyl-7-oxo-1,2,3,4,4a,7 8,8a-octahydronaphthalen-1-yl)-ethyl]-5H-furan-2-one of the formula 1 given below or pharmaceutically acceptable derivatives thereof, isolated from Gomphostema niveum and also provides a...

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Hauptverfasser: PRASANNA, SUBRAMANIAM, THAVASELVAM, DURAIPANDIAN, NIVSARKAR, MANISHA, SEKHAR, KRISHNAMURTHY, ACHARYA, BADRI NARAYAN, KAUSHIK, MAHABIR PRASHAD
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides an antimalarial compound 3-[2-(2-Hydroxymethyl-1,4a,5-trimethyl-7-oxo-1,2,3,4,4a,7 8,8a-octahydronaphthalen-1-yl)-ethyl]-5H-furan-2-one of the formula 1 given below or pharmaceutically acceptable derivatives thereof, isolated from Gomphostema niveum and also provides a method for the extraction thereof as well as methods for the treatment of malaria using said compound.