METHODS AND COMPOSITION TO GENERATE UNIQUE SEQUENCE DNA PROBES LABELING OF DNA PROBES AND THE USE OF THESE PROBES

The invention relates generally to the field of identification of DNA sequences, genes or chromosomes. Methods and composition to obtain Unique Sequence DNA probes are provided. Composition comprises of any double stranded DNA containing Unique Sequences from which the repetitive sequences are elimi...

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Hauptverfasser: TERSTAPPEN, LEON W. M. M, SWENNENHUIS, JOOST F, FOULK, BRAD, CONNELLY, MARK CARLE, KAGAN, MICHAEL T, TIBBE, ARJAN G. J, VERRANT, JOHN A
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates generally to the field of identification of DNA sequences, genes or chromosomes. Methods and composition to obtain Unique Sequence DNA probes are provided. Composition comprises of any double stranded DNA containing Unique Sequences from which the repetitive sequences are eliminated according to the method described in this invention. The invention also relates to the preservation of cells that have been identified after immunomagnetic selection and fluorescent labeling in order to further interrogate the cells of interest. Furthermore the invention relates to genetic analysis of cells that have been identified after immunomagnetic selection and fluorescent labeling.