NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the foll...

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Bibliographische Detailangaben
Hauptverfasser: SASAKI, TOSHINOBU, TAKEDA, MASAKAZU, TOYOSHIMA, TAKAHIRO, HOSHINO, CHIKARA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y 1 represents N or C(R 4 ) ; Y 2 represents N or C(R 5 ) ; R 4 and R 5 independently represent an alkyl group, a hydrogen atom etc. ; one of R 1 and R 2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R 1 and R 2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R 3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient.