HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X is -C(=O)NHR4, or CH2-het; R1, R2, R3 are independently H or F; R4 is H, C1-6 alkyl, or OC1-6alkyl; het is a five (5)-membered heterocyclic ring having 1, 2 or 3 heteroatoms selected from...

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Hauptverfasser: KIM, JI-YOUNG, JOSYULA, VARA PRASAD VENKATA NAGENDRA, BOYER, FREDERICK EARL, JR
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creator KIM, JI-YOUNG
JOSYULA, VARA PRASAD VENKATA NAGENDRA
BOYER, FREDERICK EARL, JR
description The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X is -C(=O)NHR4, or CH2-het; R1, R2, R3 are independently H or F; R4 is H, C1-6 alkyl, or OC1-6alkyl; het is a five (5)-membered heterocyclic ring having 1, 2 or 3 heteroatoms selected from the group consisting of non-peroxide oxygen, sulfur, and nitrogen within the ring. The compounds of the present are useful as antibacterial agents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS
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