HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X is -C(=O)NHR4, or CH2-het; R1, R2, R3 are independently H or F; R4 is H, C1-6 alkyl, or OC1-6alkyl; het is a five (5)-membered heterocyclic ring having 1, 2 or 3 heteroatoms selected from...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, JI-YOUNG, JOSYULA, VARA PRASAD VENKATA NAGENDRA, BOYER, FREDERICK EARL, JR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X is -C(=O)NHR4, or CH2-het; R1, R2, R3 are independently H or F; R4 is H, C1-6 alkyl, or OC1-6alkyl; het is a five (5)-membered heterocyclic ring having 1, 2 or 3 heteroatoms selected from the group consisting of non-peroxide oxygen, sulfur, and nitrogen within the ring. The compounds of the present are useful as antibacterial agents.