IMMUNOLIPOSOME COMPOSITION FOR TARGETING TO A HER2 CELL RECEPTOR

IMMUNOLIPOSOME COMPOSITION FOR TARGETING TO A HER2 CELL RECEPTOR

An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapp...

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Bibliographische Detailangaben
Hauptverfasser: NAJAFI, AZAR, KELLEY, LAURA, ABRA, ROBERT, GUO, LUKE, WONG, FRANCIS M. P, HUANG, ANTHONY, HJORTSVANG, KRISTEN
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapped drug.