AN ANTIMICROBIAL AGENT COMPRISING A CYSTEINE COMPONENT COVALENTLY BOUND TO A SUBSTRATE VIA A DISULFIDE BRIDGE, A SPACER, AND A LINKING GROUP

The invention relates to an antimicrobial agent where a cysteine compound is covalently bound to a substrate, in particular by binding through an S-S bridge via a spacer molecule to the substrate. The spacer comprises a carbon chain, optionally interrupted by one or more heteroatoms, e.g. O, S, N, P...

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Bibliographische Detailangaben
Hauptverfasser:	GUDMUNDSSON, GUDMUNDUR, WIRSEN, ANDERS, AGERBERTH, BIRGITTA, LINDBERG, TORBJORN, ODEBERG, JACOB
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FISHING FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES TRAPPING TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
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Beschreibung
Zusammenfassung:	The invention relates to an antimicrobial agent where a cysteine compound is covalently bound to a substrate, in particular by binding through an S-S bridge via a spacer molecule to the substrate. The spacer comprises a carbon chain, optionally interrupted by one or more heteroatoms, e.g. O, S, N, P and Si; the chain is optionally substituted with one or more alkyl groups, preferably lower alkyl groups with 1-5 carbon atoms, hydroxyl groups or alkoxy groups. Also, the invention refers to a substrate that is coated with the antimicrobial agent of the invention. The agent has excellent antimicrobial properties and can be used to coat surfaces and substrates of various devices, such as medical devices or devices used in food handling, in order to prevent or inhibit accumulation and/or growth and/or proliferation and/or the viability of microorganisms and/or formation of biofilm. L'invention concerne un agent antimicrobien dans lequel un composé de cystéine est lié de façon covalente à un substrat, notamment, par liaison au substrat, par le biais d'un pont S-S via une molécule d'espaceur. L'espaceur comporte une chaîne de carbone, facultativement interrompue par au moins un hétéroatome, par exemple, O, S, N, P et Si, la chaîne est facultativement substituée par au moins un groupe alkyle, de préférence, des groupes alkyle inférieurs dotés de 1 à 5 atomes de carbone, des groupes hydroxyle ou des groupes alkoxy. Cette invention a aussi pour objet un substrat recouvert de l'agent antimicrobien susmentionné. Cet agent présente d'excellentes propriétés antimicrobiennes et peut être utilisé pour recouvrir des surfaces et des substrats de divers dispositifs, tels que des dispositifs médicaux ou des dispositifs utilisés dans la manipulation d'aliments, en vue de prévenir ou d'inhiber l'accumulation et/ou la croissance et/ou la prolifération et/ou la viabilité de micro-organismes et/la formation d'un biofilm.