DETECTION OF AN IMMUNE RESPONSE TO GDF-8 MODULATING AGENTS

This disclosure provides methods for the detection of antibodies to a GDF-8 modulating agent such as, e.g., MYO-029, in a biological sample. Methods to detect an immune response to a GDF-8 modulating agent are also included. In particular, methods to assess an immune response in animals, including h...

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Bibliographische Detailangaben
Hauptverfasser:	SUN, SHUJUN, CAIAZZO, TERESA M, O'HARA, DENISE M, RAJEWSKI, JOSEPH W. III, CRYAN, JOHN G, JOYCE, ALISON, NOWAK, JOHN A, WOLFMAN, NEIL M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	This disclosure provides methods for the detection of antibodies to a GDF-8 modulating agent such as, e.g., MYO-029, in a biological sample. Methods to detect an immune response to a GDF-8 modulating agent are also included. In particular, methods to assess an immune response in animals, including humans, to a GDF-8 modulating agent such as a GDF-8 inhibitor are provided herein.