STABILIZING ENZYME ACTIVITY IN ELECTROCHEMICAL BIOSENSORS

A reagent composition containing GDH-PQQ as an enzyme-co-factor and screen-printed on working and counter electrodes of electrochemical biosensors, maintains activity of the enzyme reagents by proper selection of components. A preferred composition includes hydrophilic polymers, amorphous untreated...

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Bibliographische Detailangaben
Hauptverfasser:	CHU, AMY H, SPRADLIN, HOPE G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A reagent composition containing GDH-PQQ as an enzyme-co-factor and screen-printed on working and counter electrodes of electrochemical biosensors, maintains activity of the enzyme reagents by proper selection of components. A preferred composition includes hydrophilic polymers, amorphous untreated silica, buffers, surfactants, and a mediator. For example, the biosensor is useful in the amperometric determination of glucose. La présente invention concerne une composition réactive contenant du GDH-PQQ servant de cofacteur d'enzyme. Cette composition sérigraphiée sur les électrodes directes et les contre-électrodes de biocapteurs électrochimiques, entretient l'activité des réactifs enzymatiques par une sélection appropriée des composants. Une composition préférée contient des polymères hydrophiles, de la silice amorphe non traitée, des tampons, des tensioactifs, et un médiateur.