PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE
Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 c...
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| creator | SLEEVI, MARK C KELLEY, GLEN L |
| description | Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.
La présente invention concerne des complexes de IGF-I et IGFBP-3 de trois nouveaux niveaux de pureté. L'invention concerne également des techniques chromatographiques d'élimination de contaminants tels que les variantes masse et charge d'IGFBP-3. Ces nouvelles techniques permettent la production de compositions pharmaceutiques de haute qualité comprenant des complexes IGF-I/IGFBP-3. |
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La présente invention concerne des complexes de IGF-I et IGFBP-3 de trois nouveaux niveaux de pureté. L'invention concerne également des techniques chromatographiques d'élimination de contaminants tels que les variantes masse et charge d'IGFBP-3. Ces nouvelles techniques permettent la production de compositions pharmaceutiques de haute qualité comprenant des complexes IGF-I/IGFBP-3.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151124&DB=EPODOC&CC=CA&NR=2592014C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151124&DB=EPODOC&CC=CA&NR=2592014C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SLEEVI, MARK C</creatorcontrib><creatorcontrib>KELLEY, GLEN L</creatorcontrib><title>PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE</title><description>Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.
La présente invention concerne des complexes de IGF-I et IGFBP-3 de trois nouveaux niveaux de pureté. L'invention concerne également des techniques chromatographiques d'élimination de contaminants tels que les variantes masse et charge d'IGFBP-3. Ces nouvelles techniques permettent la production de compositions pharmaceutiques de haute qualité comprenant des complexes IGF-I/IGFBP-3.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAJCA3ydPN0dVEI8vB0d9P11AfTTgG6xgrO_r4BPq4RrsEKjn4uCiEerp5BCr6uIR7-Lgr-bgq-jn6hbo7OIaFBrjwMrGmJOcWpvFCam0HezTXE2UM3tSA_PrW4IDE5NS-1JN7Z0cjU0sjA0MTZmLAKAIM4Kn4</recordid><startdate>20151124</startdate><enddate>20151124</enddate><creator>SLEEVI, MARK C</creator><creator>KELLEY, GLEN L</creator><scope>EVB</scope></search><sort><creationdate>20151124</creationdate><title>PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE</title><author>SLEEVI, MARK C ; KELLEY, GLEN L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2592014C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SLEEVI, MARK C</creatorcontrib><creatorcontrib>KELLEY, GLEN L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SLEEVI, MARK C</au><au>KELLEY, GLEN L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE</title><date>2015-11-24</date><risdate>2015</risdate><abstract>Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.
La présente invention concerne des complexes de IGF-I et IGFBP-3 de trois nouveaux niveaux de pureté. L'invention concerne également des techniques chromatographiques d'élimination de contaminants tels que les variantes masse et charge d'IGFBP-3. Ces nouvelles techniques permettent la production de compositions pharmaceutiques de haute qualité comprenant des complexes IGF-I/IGFBP-3.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PURIFIED RHIGF-I/RHIGFBP-3 COMPLEXES AND THEIR METHOD OF MANUFACTURE |
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