CHARACTERIZATION OF C19ORF10, A NOVEL SYNOVIAL PROTEIN

Immunofluorescence analysis of cultured cells suggests that the c19orf10 product is localized to the ER/golgi apparatus. The synovial tissue distribution is unique, with staining of both the synovial membrane and the perivascular regions. In some cases there also appears to be an inverse relationshi...

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Hauptverfasser:	DU, QIUJIANG, KROHKIN, OLEG, ENS, WERNER, EL-GABALAWY, HANI, DASURI, KUMAR, WILKINS, JOHN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	Immunofluorescence analysis of cultured cells suggests that the c19orf10 product is localized to the ER/golgi apparatus. The synovial tissue distribution is unique, with staining of both the synovial membrane and the perivascular regions. In some cases there also appears to be an inverse relationship between synovial hyperplasia and c19orf10 expression, raising the possibility that c19orf10 production may be lost during hyperplasia.