STEROID FORMULATION AND METHODS OF TREATMENT USING SAME

STEROID FORMULATION AND METHODS OF TREATMENT USING SAME

The invention provides steroid-containing pharmaceutical compositions which are free of classical preservatives and preferably comprise a steroid that i s sparingly soluble or substantially insoluble in water, particulate steroid having an average particle size of from about 2.2 to about 10 microns....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YUAN, PENG, CSAKY, KARL G, ROBINSON, MICHAEL R, POTTI, GOPAL K, GRAVLIN, LUISA V, GRIMES, GEORGE
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention provides steroid-containing pharmaceutical compositions which are free of classical preservatives and preferably comprise a steroid that i s sparingly soluble or substantially insoluble in water, particulate steroid having an average particle size of from about 2.2 to about 10 microns. Pharmaceutical compositions consisting essentially of particulate triamcinolone acetonide, methylcellulose or hydroxy(C1- C8)alkylmethylcellulose, an pharmaceutically acceptable salt, and water are provided by the invention, which compositions are substantially free of non- saccharide polymers and preservatives. The pharmaceutical compositions can b e used to treat medical conditions, including ophthalmological conditions and pain.