ANTHRANILAMIDE PYRIDINUREAS AS VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)RECEPTOR KINASE INHIBITORS

The invention relates to novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis. In one aspect of the invention, the anthranilamide pyridinurea compounds...

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Bibliographische Detailangaben
Hauptverfasser:	HABEREY, MARTIN, HESS-STUMPP, HOLGER, KRUEGER, MARTIN, BOHLMANN, ROLF, THIERAUCH, KARL-HEINZ, INCE, STUART, HUTH, ANDREAS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis. In one aspect of the invention, the anthranilamide pyridinurea compounds are of the general formula (I): (see formula I) or an isomer, diastereoisomer, enantiomer, tautomer or salt thereof.