TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	YING, WEIWEN, PRZEWLOKA, TERESA, CHIMMANAMADA, DINESH U, BARSOUM, JAMES, JAMES, DAVID, ZHANG, SHIJIE, FOLEY, KEVIN, CHAE, JUNGHYUN, LEE, CHI-WAN, KOSTIK, ELENA, NG, HOWARD P, DU, ZHENJIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. La présente invention concerne des composés triazole substitués et des compositions renfermant lesdits composés. L'invention concerne également des méthodes propres à inhiber l'activité de Hsp90 chez un sujet qui en a besoin et des méthodes de prévention ou de traitement de troubles hyperprolifératifs, tels que le cancer, consistant à administrer au sujet qui en a besoin un composé triazole substitué de l'invention ou une composition renfermant un tel composé.