VACCINE COMPOSITION AGAINST RHODOCOCCUS EQUI

A method for preparing a soluble antigenic extract from Rhodococcus equi is disclosed. The method includes a step of solubilizing membranes of said bacteria by contacting said bacteria with an extraction solution containing a nonionic detergent of sorbitan polyethylene fatty acid ester type. Also di...

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Bibliographische Detailangaben
Hauptverfasser:	TAOUJI, SAID, BALLET, JEAN-JACQUES, CAUCHARD, JULIEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method for preparing a soluble antigenic extract from Rhodococcus equi is disclosed. The method includes a step of solubilizing membranes of said bacteria by contacting said bacteria with an extraction solution containing a nonionic detergent of sorbitan polyethylene fatty acid ester type. Also disclosed is a soluble antigenic extract obtainable by said preparation method, said extract including membrane antigens of Rhodococcus equi dissolved in the extraction solution. Finally, a composition including the soluble antigenic extract as a medicine is disclosed, including preferably a nanoparticulate or oil-in-water emulsion type adjuvant, and the use of the soluble antigenic extract for preparing a pharmaceutical composition for preventing or treating a Rhodococcus equi-induced infection in an animal.