OXIDATIVE DEGRADATION PRODUCTS OF ATORVASTATIN CALCIUM

The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such ator...

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Bibliographische Detailangaben
Hauptverfasser: GRAHEK, ROK, KRACUN, MATJAZ, KOCJAN, DARKO, BASTARDA, ANDREJ, KOCIJAN, ANDREJ
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such atorvastatin calcium. L'invention concerne des produits de dégradation oxydante du calcium d'atorvastatine et le procédé de préparation de ceux-ci. L'invention concerne également du calcium d'atorvastatine sensiblement exempt de produits de dégradation oxydante et les compositions pharmaceutiques renfermant un tel calcium d'atorvastatine.