GENDER SELECTION WITH THE USE OF ANTIBODIES

Epitope polypeptides, corresponding to antigenic regions of hydrophilic sequences selected from within mammalian gene Y-chromosome protein sequences, have been prepared and used to generate antibodies in vivo. The antibodies have been found to bind preferentially to the Y-chromosomal sperm component...

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Hauptverfasser: AKHAVIEN-MOHAMMADI, AZARM, CARRIER, DANIELLE, LETELLIER, ROBERT, HURNIK, DANIEL, FILION, LIONEL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Epitope polypeptides, corresponding to antigenic regions of hydrophilic sequences selected from within mammalian gene Y-chromosome protein sequences, have been prepared and used to generate antibodies in vivo. The antibodies have been found to bind preferentially to the Y-chromosomal sperm component in semen. The binding has been found sufficient to decrease motility of such Y-chromosomal sperm component leading to substantial increases in female offspring when using the treated semen in artificial insemination.